Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | MDM4 | O15151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17747064 | 1.00 | KMT2A (0.52) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL17747076 | 1.00 | KMT2A (0.52) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL26513050 | 1.00 | KMT2A (0.52) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL17747075 | 1.00 | KMT2A (0.52) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL17747066 | 1.00 | KMT2A (0.52) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL26512809 | 0.93 | TLR2 (0.56) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL26512754 | 0.93 | TLR2 (0.56) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL26512797 | 0.93 | TLR2 (0.56) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL17747016 | 0.91 | KMT2A (0.55) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL30608472 | 0.91 | KMT2A (0.55) | KMT2ATLR2MDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192873-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-05 | — | — | WO | disclosed |