Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | WHR1 | P49842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26512865 | 0.92 | SCN9A (0.33) | SCN9A | |
| SCHEMBL26512969 | 0.92 | WHR1 (0.38) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL26512710 | 0.91 | HSP90AA1 (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL26512984 | 0.90 | MEN1 (0.31) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL26512924 | 0.90 | HSP90AA1 (0.31) | HSP90AA1WHR1 | |
| SCHEMBL26512972 | 0.89 | MAPT (0.34) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL26512977 | 0.87 | — | — | |
| SCHEMBL26512920 | 0.87 | ABCG2 (0.31) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL26512983 | 0.85 | MEN1 (0.32) | KDM4EMEN1ALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL25600051 | 0.83 | PDK2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |