SCHEMBL2651406

SCHEMBL2651406

O=C(O)CCNC(=O)c1ccc(CN(c2ccc(Cl)cc2)c2nc(-c3ccc(C(F)(F)F)cc3)cs2)cc1.O=C(O)CCNC(=O)c1ccc(CN(c2ccc(Cl)cc2)c2nc(-c3ccc(OC(F)(F)F)cc3)cs2)cc1

nearest known ligand 0.94

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.94
GIPR P48546 20/20 0.94

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2647625 0.97 GCGR (1.00) GCGRGIPR
SCHEMBL2648715 0.97 GCGR (1.00) GCGRGIPR
SCHEMBL2648635 0.96 GCGR (1.00) GCGRGIPR
SCHEMBL2649736 0.94 GCGR (1.00) GCGRGIPR
SCHEMBL2647037 0.94 GCGR (1.00) GCGRGIPR
SCHEMBL2665890 0.94 GCGR (1.00) GCGRGIPR
SCHEMBL2647489 0.93 GCGR (0.94) GCGRGIPR
SCHEMBL2665785 0.90 GCGR (0.88) GCGRGIPR
SCHEMBL2646896 0.90 GCGR (0.88) GCGRGIPR
SCHEMBL2648158 0.90 GCGR (0.88) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004063147-A1 SALTS AND SOLVATES OF GLUCAGON ANTAGONISTS NOVO NORDISK A/S (DK) 2004-07-29 WO disclosed