Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342633 | 0.94 | TP53 (0.47) | TP53GAAMAPTLMNAHTT | |
| SCHEMBL1343305 | 0.93 | GAA (0.48) | TP53GAAMAPTLMNAHTT | |
| SCHEMBL2651424 | 0.93 | GAA (0.40) | TP53GAAMAPTLMNAHTT | |
| SCHEMBL1342775 | 0.88 | TP53 (0.44) | TP53GAAMAPTLMNAHTT | |
| SCHEMBL1343267 | 0.87 | TP53 (0.44) | TP53GAAMAPTLMNAHTT | |
| SCHEMBL1343456 | 0.83 | TP53 (0.43) | TP53GAAMAPTLMNAHTT | |
| SCHEMBL1343692 | 0.82 | TP53 (0.42) | TP53GAAMAPTLMNAHTT | |
| SCHEMBL1342445 | 0.82 | TP53 (0.44) | TP53GAAMAPTLMNAHTT | |
| SCHEMBL1344127 | 0.80 | TP53 (0.47) | TP53GAAMAPTLMNAHTT | |
| SCHEMBL1342456 | 0.80 | TP53 (0.44) | TP53GAAMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |