SCHEMBL26515

SCHEMBL26515

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.61
HINT1 P49773 5/20 0.59
NT5E P21589 1/20 0.57
TAS1R3 Q7RTX0 1/20 0.54
TAS1R1 Q7RTX1 1/20 0.54
GSK3A P49840 2/20 0.54
RPS6KA3 P51812 2/20 0.54
MAPK14 Q16539 2/20 0.54
PNP P00491 2/20 0.53
ADORA2A P29274 1/20 0.53
ADORA2B P29275 1/20 0.53
TGM2 P21980 1/20 0.53
PAX8 Q06710 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1744361 1.00 HPGD (0.61) HPGDHINT1NT5ETAS1R3TAS1R1
SCHEMBL222316 1.00 HPGD (0.61) HPGDHINT1NT5ETAS1R3TAS1R1
SCHEMBL12031119 1.00 HPGD (0.61) HPGDHINT1NT5ETAS1R3TAS1R1
SCHEMBL16198946 1.00 HPGD (0.61) HPGDHINT1NT5ETAS1R3TAS1R1
SCHEMBL12150640 1.00 HPGD (0.61) HPGDHINT1NT5ETAS1R3TAS1R1
SCHEMBL12300426 1.00 HPGD (0.61) HPGDHINT1NT5ETAS1R3TAS1R1
SCHEMBL16360143 1.00 HPGD (0.61) HPGDHINT1NT5ETAS1R3TAS1R1
SCHEMBL3713950 1.00 HPGD (0.61) HPGDHINT1NT5ETAS1R3TAS1R1
SCHEMBL18512866 1.00 HPGD (0.61) HPGDHINT1NT5ETAS1R3TAS1R1
Water SCHEMBL25345533 0.99 HPGD (0.60) HPGDHINT1NT5ETAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6173 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095093-A RNAi agents for inhibiting expression of inhibin subunit beta E (INHBE), pharmaceutical compositions and methods of use 2026-05-26 CN claimed
US-20260139251-A1 RNAi Agents for Inhibiting Expression of Mucin 5AC (MUC5AC), Compositions Thereof, and Methods of Use ARROWHEAD PHARMACEUTICALS INC (US) 2026-05-21 US claimed
US-20260132406-A1 RNAi Agents for Inhibiting Expression of Activin Receptor-Like Kinase 7 (ALK7), Compositions Thereof, and Methods of Use ARROWHEAD PHARMACEUTICALS INC (US) 2026-05-14 US claimed
EP-4739343-A2 CIRCULAR RNA VACCINES FOR SEASONAL FLU AND METHODS OF USES Shanghai Circode Biomed Co., Ltd (CN) 2026-05-13 EP claimed
EP-3826720-B1 NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF TMPRSS6 AND IRON CHELATORS SILENCE THERAPEUTICS GMBH (DE) 2026-04-22 EP claimed
EP-4722363-A1 RNAI AGENT FOR INHIBITING ANGPTL3 EXPRESSION AND USE THEREOF YUN HO BIO CO., LTD (CN) 2026-04-08 EP claimed
US-20260092276-A1 Carbohydrate-oligonucleotide conjugates, pharmaceutical compositions, and therapeutic applications KYLONOVA XIAMEN BIOPHARMA CO LTD (CN) 2026-04-02 US claimed
US-12582668-B2 Methods for the treatment of alpha-1 antitrypsin deficiency (AATD) Arrowhead Pharmaceuticals, Inc. (US) 2026-03-24 US claimed
US-20260078375-A1 RNAi Agents for Inhibiting Influenza A Viral Gene Expression, Compositions Thereof, and Methods of Use ARROWHEAD PHARMACEUTICALS INC (US) 2026-03-19 US claimed
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP claimed
US-20030204078-A1 Chemical synthesis of methoxy nucleosides RIBOZYME PHARMACEUTICALS, INC. 2003-10-30 US claimed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
US-6495675-B1 BINDS PB2 PROTEIN OF RNA POLYMERASE CHIBA INSTITUTE OF TECHNOLOGY (JP) 2002-12-17 US claimed
WO-2002057425-A2 NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE MERCK & CO., INC. (US) 2002-07-25 WO claimed
EP-1108724-A2 Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules RIBOZYME PHARMACEUTICALS, INC. (US) 2001-06-20 EP claimed
US-5962675-A Chemical syntheses of 2'-O-methoxy purine nucleosides RIBOZYME PHARMACEUTICALS, INC. (US) 1999-10-05 US claimed
EP-0795029-A1 CHEMICAL LABELLING OF OBJECTS Pabio (NO) 1997-09-17 EP claimed
WO-1996041812-A1 OLIGONUCLEOTIDE PHOSPHORYLATION METHOD AND PRODUCTS ISIS INNOVATION LIMITED (GB) 1996-12-27 WO claimed
WO-1996017954-A1 CHEMICAL LABELLING OF OBJECTS PABIO (DK) 1996-06-13 WO claimed
EP-0391411-A2 3'-Substituted methyl nucleosides as antiviral agents Bristol-Myers Squibb Company (US) 1990-10-10 EP claimed