Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 17/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26522373 | 0.88 | KCNJ1 (0.35) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| SCHEMBL30570146 | 0.79 | KCNJ1 (0.32) | KCNJ1KCNH2 | |
| SCHEMBL31380532 | 0.76 | PARP1 (0.38) | — | |
| SCHEMBL31457911 | 0.72 | TSHR (0.40) | KCNJ1 | |
| SCHEMBL30520321 | 0.71 | HTR2B (0.43) | — | |
| SCHEMBL31169182 | 0.71 | HTR2A (0.32) | — | |
| SCHEMBL26135158 | 0.70 | TSHR (0.38) | KCNJ1 | |
| SCHEMBL14530125 | 0.69 | AKT1 (0.35) | — | |
| SCHEMBL30570070 | 0.68 | CRBN (0.52) | — | |
| SCHEMBL30720208 | 0.68 | CRBN (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183607-A1 | CEREBLON LIGANDS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023183540-A1 | IKZF2 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-09-28 | — | — | WO | disclosed |