Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 3/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29741178 | 1.00 | KDM4E (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL9449076 | 0.98 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL2651055 | 0.86 | CCR1 (0.40) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL27792926 | 0.84 | KDM4E (0.64) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL31267979 | 0.83 | CNR2 (0.49) | KDM4ECYP1A2POLBBLMCNR2 | |
| SCHEMBL8936053 | 0.83 | KDM4E (0.47) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL9715965 | 0.81 | KDM4E (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL12470406 | 0.80 | KDM4E (0.43) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29761073 | 0.80 | GRM5 (0.43) | CYP1A2GRM5CNR2ALDH1A1HPGD | |
| SCHEMBL18411456 | 0.80 | KDM4E (0.52) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105336-A | Viologen derivative electrochromic material and preparation method thereof | 华南理工大学 | 2019-08-09 | — | — | CN | claimed |
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |
| CN-109679129-B | Method for modifying surface of polyolefin material | 宿迁市南京工业大学新材料研究院 | 2021-06-29 | — | — | CN | disclosed |
| CN-104961677-A | 11beta-HSD1 inhibitor of cyanobipyridine tert-alcohol structure and application of 11beta-HSD1 inhibitor | FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |
| CN-104961677-A | 11beta-HSD1 inhibitor of cyanobipyridine tert-alcohol structure and application of 11beta-HSD1 inhibitor | FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |
| EP-1383768-A1 | IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002076983-A1 | IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2002-10-03 | — | — | WO | disclosed |