Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342082 | 0.88 | MEN1 (0.42) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2651682 | 0.87 | MEN1 (0.39) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1343009 | 0.80 | MAPT (0.41) | LMNAPOLBTP53MAPTPIM1 | |
| SCHEMBL1341870 | 0.79 | POLB (0.39) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1342071 | 0.77 | POLB (0.46) | LMNAPOLBTP53MAPTPIM1 | |
| SCHEMBL1341384 | 0.76 | MAPT (0.43) | POLBTP53MAPTPIM1PIM3 | |
| SCHEMBL1343299 | 0.76 | PIM1 (0.43) | LMNAMEN1KMT2APOLBTP53 | |
| SCHEMBL1340543 | 0.74 | PIM1 (0.42) | LMNAPOLBTP53MAPTPIM1 | |
| SCHEMBL1341869 | 0.74 | MEN1 (0.41) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2649086 | 0.73 | POLB (0.43) | LMNAPOLBTP53MAPTPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |