Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343263 | 0.99 | NTRK1 (0.34) | PRMT5WDR77NTRK1NTRK2MAPT | |
| SCHEMBL1341372 | 0.94 | NTRK1 (0.34) | NTRK1NTRK2MAPTALDH1A1GCK | |
| SCHEMBL1341350 | 0.90 | GSK3B (0.35) | PRMT5WDR77NTRK1NTRK2MAPT | |
| SCHEMBL1342304 | 0.90 | NTRK1 (0.34) | PRMT5WDR77NTRK1NTRK2MAPT | |
| SCHEMBL1342555 | 0.90 | MAPT (0.38) | PRMT5WDR77MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1342995 | 0.90 | MAPT (0.34) | PRMT5WDR77NTRK1NTRK2MAPT | |
| SCHEMBL1340106 | 0.88 | NTRK1 (0.36) | NTRK1NTRK2MAPTALDH1A1RXFP1 | |
| SCHEMBL1340938 | 0.88 | GCK (0.33) | MAPTGCKKMT2A | |
| SCHEMBL1342421 | 0.87 | CCNE1 (0.33) | PRMT5WDR77NTRK1NTRK2 | |
| SCHEMBL1342541 | 0.87 | NTRK1 (0.33) | NTRK1NTRK2MAPTALDH1A1GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |