⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22813394 | 1.00 | — | — | |
| SCHEMBL17348570 | 0.91 | — | — | |
| SCHEMBL15927296 | 0.91 | — | — | |
| SCHEMBL16659522 | 0.83 | — | — | |
| SCHEMBL16659517 | 0.79 | — | — | |
| SCHEMBL16659516 | 0.78 | — | — | |
| SCHEMBL23083352 | 0.78 | SLC6A2 (0.38) | — | |
| SCHEMBL23083342 | 0.78 | SLC6A2 (0.38) | — | |
| SCHEMBL22642378 | 0.76 | HRH3 (0.33) | — | |
| SCHEMBL27115295 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| WO-2023192375-A1 | HSD17B13 INHIBITORS AND USES THEREOF | FL2022-001, INC. (US) | 2023-10-05 | — | — | WO | disclosed |