Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 10/20 | 0.50 |
| ▸ | GIPR | P48546 | 2/20 | 0.50 |
| ▸ | GLP1R | P43220 | 1/20 | 0.50 |
| ▸ | GCG | P01275 | 10/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652086 | 0.92 | GCGR (0.42) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2653111 | 0.85 | PPARD (0.40) | — | |
| SCHEMBL2274070 | 0.83 | GCGR (0.49) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2274074 | 0.83 | GCGR (0.49) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2276673 | 0.83 | GCGR (0.49) | GCGRGIPRGLP1RGCG | |
| SCHEMBL14184604 | 0.78 | GCGR (0.51) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2270697 | 0.78 | GCGR (0.54) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2270701 | 0.78 | GCGR (0.54) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2272009 | 0.78 | GCGR (0.54) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2268254 | 0.77 | GCGR (0.54) | GCGRGIPRGLP1RGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758859-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2005118542-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-15 | — | — | WO | claimed |
| EP-1758859-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005118542-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-15 | — | — | WO | disclosed |