Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 15/20 | 0.38 |
| ▸ | JAK1 | P23458 | 8/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24498338 | 0.89 | TYK2 (0.46) | TYK2JAK1 | |
| SCHEMBL26522163 | 0.88 | TYK2 (0.34) | TYK2JAK1JAK2JAK3MAP4K4 | |
| SCHEMBL24498409 | 0.83 | PIK3C3 (0.37) | TYK2JAK1JAK2JAK3 | |
| SCHEMBL24498550 | 0.81 | TYK2 (0.42) | TYK2JAK1JAK2SYK | |
| SCHEMBL24498193 | 0.80 | TYK2 (0.48) | TYK2JAK1 | |
| SCHEMBL29684805 | 0.80 | TYK2 (0.48) | TYK2JAK1 | |
| SCHEMBL26522201 | 0.80 | TYK2 (0.40) | TYK2JAK1JAK2JAK3SYK | |
| SCHEMBL26532688 | 0.79 | JAK1 (0.42) | TYK2JAK1JAK2JAK3IRAK4 | |
| SCHEMBL26522858 | 0.79 | TYK2 (0.42) | TYK2JAK1 | |
| SCHEMBL24498431 | 0.78 | DHODH (0.36) | TYK2JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257587-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |