Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341143 | 0.92 | POLB (0.46) | POLBMAPTTP53MAPK14NPSR1 | |
| SCHEMBL1342694 | 0.91 | POLB (0.47) | POLBMAPTTP53MAPK14NPSR1 | |
| SCHEMBL1343201 | 0.90 | POLB (0.48) | POLBMAPTTP53DHODHNPSR1 | |
| SCHEMBL1342394 | 0.84 | POLB (0.42) | POLBMAPTTP53MAPK14DHODH | |
| SCHEMBL1343249 | 0.82 | POLB (0.43) | POLBMAPTTP53NPSR1L3MBTL1 | |
| SCHEMBL1343252 | 0.81 | POLB (0.44) | POLBMAPTTP53NPSR1L3MBTL1 | |
| SCHEMBL1341038 | 0.81 | F10 (0.41) | POLBMAPTTP53L3MBTL1MEN1 | |
| SCHEMBL1343212 | 0.81 | MAPT (0.41) | POLBMAPTTP53MAPK14DHODH | |
| SCHEMBL6695568 | 0.80 | POLB (0.40) | POLBMAPTTP53DHODHNPSR1 | |
| SCHEMBL1343250 | 0.80 | POLB (0.40) | POLBMAPTTP53DHODHNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |