Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.40 |
| ▸ | JAK1 | P23458 | 12/20 | 0.40 |
| ▸ | JAK2 | O60674 | 11/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29685289 | 0.97 | TYK2 (0.41) | TYK2JAK1JAK2KCNH2PDE4D | |
| SCHEMBL26120767 | 0.97 | TYK2 (0.41) | TYK2JAK1JAK2KCNH2PDE4D | |
| SCHEMBL26522804 | 0.92 | TYK2 (0.39) | TYK2JAK1JAK2KCNH2PDE4D | |
| SCHEMBL26522789 | 0.92 | TYK2 (0.39) | TYK2JAK1JAK2KCNH2PDE4D | |
| SCHEMBL26522698 | 0.92 | TYK2 (0.45) | TYK2JAK1JAK2KCNH2PDE4D | |
| SCHEMBL29684948 | 0.91 | TYK2 (0.44) | TYK2JAK1JAK2KCNH2PDE4D | |
| SCHEMBL26117687 | 0.91 | TYK2 (0.44) | TYK2JAK1JAK2KCNH2PDE4D | |
| SCHEMBL26534722 | 0.90 | TYK2 (0.44) | TYK2JAK1JAK2KCNH2JAK3 | |
| SCHEMBL24498424 | 0.89 | TYK2 (0.40) | TYK2JAK1JAK2KCNH2PDE4D | |
| SCHEMBL29685758 | 0.89 | TYK2 (0.41) | TYK2JAK1JAK2KCNH2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257587-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |