SCHEMBL265246

SCHEMBL265246

N#C[PH](=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101006-A1 PROCESS FOR THE SYNTHESIS OF PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS NOVARTIS AG (CH) 2025-03-27 US disclosed
EP-4472969-A1 PROCESS FOR THE SYNTHESIS OF PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS Novartis AG (CH) 2024-12-11 EP disclosed
CN-118871436-A Synthesis of pyrazolyl derivatives useful as anticancer agents 诺华股份有限公司 2024-10-29 CN disclosed
WO-2023143605-A1 PROCESS FOR THE SYNTHESIS OF PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS NOVARTIS AG (CH) 2023-08-03 WO disclosed
EP-3297991-B1 NOVEL AMIDOHETEROARYL AROYL HYDRAZIDE ETHYNES SUN PHARMA ADVANCED RES CO LTD (IN) 2020-01-29 EP disclosed
US-10150733-B2 Amidoheteroaryl aroyl hydrazide ethynes SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) 2018-12-11 US disclosed
US-20180127372-A1 NOVEL AMIDOHETEROARYL AROYL HYDRAZIDE ETHYNES SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) 2018-05-10 US disclosed
EP-3297991-A1 NOVEL AMIDOHETEROARYL AROYL HYDRAZIDE ETHYNES Sun Pharma Advanced Research Company Ltd (IN) 2018-03-28 EP disclosed
EP-2665709-B1 DIARYLACETYLENE HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS SUN PHARMA ADVANCED RES CO LTD (IN) 2016-12-07 EP disclosed
WO-2016185490-A1 NOVEL AMIDOHETEROARYL AROYL HYDRAZIDE ETHYNES SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2016-11-24 WO disclosed
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates EPOCH BIOSCIENCES, INC. (US) 2007-07-26 US disclosed
US-20070093506-A1 Inhibitors of tyrosine kinases BREITENSTEIN WERNER 2007-04-26 US disclosed
US-7169791-B2 Inhibitors of tyrosine kinases NOVARTIS AG (CH) 2007-01-30 US disclosed
US-20060167015-A1 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol1yl)-3-(trifluoromethyl)phenyl]benzamide or an N-oxide or salts; anticarcinogenic agent (leukaemia) NOVARTIS AG (CH) 2006-07-27 US disclosed
US-20060142577-A1 Novel pyrimidineamide derivatives and the use thereof NOVARTIS AG (CH) 2006-06-29 US disclosed
EP-1546127-A1 NOVEL PYRIMIDINEAMIDE DERIVATIVES AND THE USE THEREOF Novartis AG (CH) 2005-06-29 EP disclosed
EP-1532138-A1 INHIBITORS OF TYROSINE KINASES Novartis AG (CH) 2005-05-25 EP disclosed
WO-2004029038-A1 NOVEL PYRIMIDINEAMIDE DERIVATIVES AND THE USE THEREOF NOVARTIS AG (CH) 2004-04-08 WO disclosed
WO-2004005281-A1 INHIBITORS OF TYROSINE KINASES NOVARTIS AG (CH) 2004-01-15 WO disclosed
WO-1998038168-A1 ISOQUINOLINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS TANABE SEIYAKU CO., LTD. (JP) 1998-09-03 WO disclosed