Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.52 |
| ▸ | GIPR | P48546 | 4/20 | 0.49 |
| ▸ | GLP1R | P43220 | 2/20 | 0.49 |
| ▸ | GCG | P01275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2271871 | 0.97 | GCGR (0.48) | GCGRGIPRGLP1R | |
| SCHEMBL2273243 | 0.97 | GCGR (0.48) | GCGRGIPRGLP1R | |
| SCHEMBL2276092 | 0.94 | GCGR (0.55) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2276091 | 0.94 | GCGR (0.55) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2269762 | 0.87 | GCGR (0.53) | GCGRGIPR | |
| SCHEMBL2270627 | 0.86 | GCGR (0.59) | GCGRGIPR | |
| SCHEMBL2270623 | 0.86 | GCGR (0.59) | GCGRGIPR | |
| SCHEMBL1765733 | 0.85 | GCGR (0.54) | GCGRGIPRGLP1RGCG | |
| SCHEMBL1765515 | 0.84 | GCGR (0.45) | GCGRGIPRGLP1RGCG | |
| SCHEMBL1765760 | 0.84 | GCGR (0.55) | GCGRGIPRGLP1RGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758859-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005118542-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-15 | — | — | WO | disclosed |