Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.69 |
| ▸ | INSR | P06213 | 2/20 | 0.63 |
| ▸ | IGF1R | P08069 | 2/20 | 0.63 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24179305 | 0.94 | EGFR (0.78) | EGFRINSRIGF1RALK | |
| SCHEMBL30216884 | 0.94 | EGFR (0.78) | EGFRINSRIGF1RALK | |
| Water SCHEMBL28998104 | 0.93 | EGFR (0.77) | EGFRINSRIGF1RALK | |
| SCHEMBL24178971 | 0.92 | EGFR (0.66) | EGFRINSRIGF1RALK | |
| SCHEMBL24178968 | 0.91 | EGFR (0.67) | EGFRINSRIGF1RALK | |
| SCHEMBL24179083 | 0.89 | EGFR (0.77) | EGFRINSRIGF1RALK | |
| SCHEMBL24179046 | 0.89 | EGFR (0.74) | EGFRINSRIGF1RALK | |
| SCHEMBL24179102 | 0.89 | EGFR (0.70) | EGFRINSRIGF1RALK | |
| SCHEMBL24179124 | 0.87 | ALK (0.74) | EGFRINSRIGF1RALK | |
| SCHEMBL24178910 | 0.87 | EGFR (0.66) | EGFRINSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322822-A1 | ARYL PHOSPHOROUS OXIDE COMPOUNDS AND USE THEREOF | CHENGDU DI'AO JIUHONG PHARMACEUTICAL FACTORY (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322822-A1 | ARYL PHOSPHOROUS OXIDE COMPOUNDS AND USE THEREOF | ALK, EGFR, ROS1 | EGFR 2/4885INSR 550/4885IGF1R 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.