Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 10/20 | 0.60 |
| ▸ | EGFR | P00533 | 7/20 | 0.60 |
| ▸ | EML4 | Q9HC35 | 6/20 | 0.60 |
| ▸ | INSR | P06213 | 5/20 | 0.50 |
| ▸ | IGF1R | P08069 | 4/20 | 0.50 |
| ▸ | MAP4K1 | Q92918 | 8/20 | 0.49 |
| ▸ | ROS1 | P08922 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | FER | P16591 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | BLK | P51451 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.46 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.46 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24179401 | 0.88 | ALK (0.63) | ALKEGFREML4INSRIGF1R | |
| SCHEMBL24178918 | 0.88 | EGFR (0.50) | ALKEGFREML4INSRIGF1R | |
| SCHEMBL26473441 | 0.85 | EGFR (0.50) | ALKEGFREML4INSRIGF1R | |
| SCHEMBL26528462 | 0.85 | ALK (0.56) | ALKINSRIGF1RMAP4K1 | |
| SCHEMBL15600965 | 0.84 | ALK (0.62) | ALKEGFREML4INSRIGF1R | |
| SCHEMBL13832329 | 0.84 | ALK (0.62) | ALKEGFREML4INSRIGF1R | |
| SCHEMBL15600979 | 0.84 | ALK (0.61) | ALKEGFREML4INSRIGF1R | |
| SCHEMBL24178967 | 0.84 | EGFR (0.84) | ALKEGFREML4INSRIGF1R | |
| SCHEMBL17792771 | 0.82 | EGFR (0.53) | ALKEGFREML4INSRIGF1R | |
| SCHEMBL26528471 | 0.80 | ALK (0.64) | ALKEGFREML4INSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322822-A1 | ARYL PHOSPHOROUS OXIDE COMPOUNDS AND USE THEREOF | CHENGDU DI'AO JIUHONG PHARMACEUTICAL FACTORY (CN) | 2023-10-12 | — | — | US | disclosed |
| US-20230322822-A1 | ARYL PHOSPHOROUS OXIDE COMPOUNDS AND USE THEREOF | CHENGDU DI'AO JIUHONG PHARMACEUTICAL FACTORY (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322822-A1 | ARYL PHOSPHOROUS OXIDE COMPOUNDS AND USE THEREOF | ALK, EGFR, ROS1 | ALK 1/4885EGFR 2/4885EML4 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.