Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 11/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29582204 | 1.00 | MAPT (0.52) | MAPTLCKDYRK1AKDM4EMEN1 | |
| SCHEMBL23974266 | 0.84 | LCK (0.56) | MAPTLCKDYRK1AKDM4EMEN1 | |
| SCHEMBL29454481 | 0.84 | LCK (0.56) | MAPTLCKDYRK1AKDM4EMEN1 | |
| SCHEMBL1284899 | 0.83 | MAPT (0.76) | MAPTLCKKDM4EMEN1HPGD | |
| SCHEMBL23183609 | 0.83 | DYRK1A (0.67) | MAPTLCKDYRK1A | |
| SCHEMBL1284898 | 0.81 | MAPT (0.55) | MAPTLCKDYRK1A | |
| SCHEMBL3283781 | 0.81 | MAPT (0.55) | MAPTLCKDYRK1A | |
| SCHEMBL3224565 | 0.81 | MAPT (0.52) | MAPTLCKDYRK1AMEN1KMT2A | |
| SCHEMBL21821684 | 0.81 | MAPT (0.50) | MAPTDYRK1AKDM4EMEN1HPGD | |
| SCHEMBL3053547 | 0.81 | DYRK1A (0.70) | MAPTLCKDYRK1AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969904-A | Compounds useful as autophagy modulators, methods of preparation and uses thereof | 微境生物医药科技(上海)有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-111148740-B | Compounds useful as autophagy modulators, methods of preparation and uses thereof | 微境生物医药科技(上海)有限公司 | 2023-08-25 | — | — | CN | disclosed |