Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 9/20 | 0.53 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.50 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.50 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.50 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.50 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.50 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.50 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.50 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.50 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6758435 | 0.89 | GCGR (0.54) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2647004 | 0.88 | GCGR (0.55) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2653780 | 0.88 | GCGR (0.55) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2647509 | 0.88 | GCGR (0.55) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2654410 | 0.88 | GCGR (0.54) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2648741 | 0.88 | GCGR (0.54) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2648467 | 0.88 | GCG (0.53) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2653941 | 0.88 | GCGR (0.50) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2660123 | 0.88 | GCG (0.49) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2653505 | 0.87 | GCGR (0.45) | GCGRCA12CA1CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152750-A1 | Novel glucagon antagonists | NOVO NORDISK A/S (DK) | 2004-08-05 | — | — | US | disclosed |
| WO-2004056763-A2 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152750-A1 | Novel glucagon antagonists | GLP1R, GCGR, GIPR | GCGR 2/4885ADCY6 615/4885ADCY3 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.