Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 8/20 | 0.44 |
| ▸ | GIPR | P48546 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2656779 | 0.89 | PSEN1 (0.53) | PPARDPPARAGCGRGIPR | |
| SCHEMBL2652886 | 0.86 | MEN1 (0.55) | MEN1KMT2AEPHX2GCGRGIPR | |
| SCHEMBL2661613 | 0.86 | MEN1 (0.55) | MEN1KMT2AEPHX2GCGRGIPR | |
| SCHEMBL2652235 | 0.86 | MEN1 (0.55) | MEN1KMT2AEPHX2GCGRGIPR | |
| SCHEMBL2654985 | 0.86 | MEN1 (0.55) | MEN1KMT2AEPHX2GCGRGIPR | |
| SCHEMBL2653662 | 0.86 | MEN1 (0.55) | MEN1KMT2AEPHX2GCGRGIPR | |
| SCHEMBL2654122 | 0.86 | MEN1 (0.55) | MEN1KMT2AEPHX2GCGRGIPR | |
| SCHEMBL2653574 | 0.86 | MEN1 (0.55) | MEN1KMT2AEPHX2GCGRGIPR | |
| SCHEMBL2654583 | 0.86 | MEN1 (0.55) | MEN1KMT2AEPHX2GCGRGIPR | |
| SCHEMBL2654850 | 0.86 | GCGR (0.53) | MEN1KMT2APPARDPPARAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758853-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123668-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-29 | — | — | WO | disclosed |