SCHEMBL26534382

SCHEMBL26534382

O=C(Nc1ncnc2c([C@H]3C[C@H](O)[C@@H](CO)O3)snc12)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GALR3 O60755 1/20 0.41
▸ NR2F2 P24468 1/20 0.41
▸ ADK P55263 1/20 0.36
▸ BRD4 O60885 1/20 0.35
▸ NCOA1 Q15788 1/20 0.35
▸ NCOA3 Q9Y6Q9 1/20 0.35
▸ CSF1R P07333 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ ADORA1 P30542 1/20 0.34
▸ LGALS9 O00182 1/20 0.34
▸ LGALS1 P09382 1/20 0.34
▸ LGALS3 P17931 1/20 0.34
▸ LGALS7; LGALS7B P47929 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26534380 0.92 BRD4 (0.35) GALR3NR2F2BRD4CSF1RADORA1
SCHEMBL26533894 0.84 GALR3 (0.44) GALR3NR2F2ADKBRD4NCOA1
SCHEMBL26534727 0.82 TYMP (0.39) BRD4ADORA1
SCHEMBL26533899 0.76 GALR3 (0.36) GALR3NR2F2BRD4CSF1R
SCHEMBL25399504 0.74 TMPRSS2 (0.44) GALR3NR2F2ADKBRD4POLB
SCHEMBL264408 0.74 SLC29A1 (0.59) —
SCHEMBL29674600 0.74 SLC29A1 (0.59) —
SCHEMBL21539907 0.74 SLC29A1 (0.59) —
SCHEMBL22984010 0.74 SLC29A1 (0.59) —
SCHEMBL264409 0.74 SLC29A1 (0.59) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787833-B2 Modified cyclic dinucleoside compounds as sting modulators ALIGOS THERAPEUTICS, INC. (US) 2023-10-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11787833-B2 Modified cyclic dinucleoside compounds as sting modulators STING1, CGAS, IRF3 GALR3 1461/4885NR2F2 661/4885ADK 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback