⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26537621 | 1.00 | — | — | |
| SCHEMBL750103 | 1.00 | — | — | |
| SCHEMBL12253464 | 0.97 | — | — | |
| SCHEMBL1921189 | 0.82 | — | — | |
| SCHEMBL910644 | 0.79 | DPP4 (0.36) | — | |
| SCHEMBL9732460 | 0.78 | — | — | |
| SCHEMBL17510167 | 0.76 | EPHX2 (0.30) | — | |
| SCHEMBL337473 | 0.76 | EPHX2 (0.30) | — | |
| SCHEMBL16977501 | 0.76 | EPHX2 (0.30) | — | |
| SCHEMBL14088213 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308562-A1 | PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2024-01-24 | — | — | EP | disclosed |
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | NOVARTIS AG (CH) | 2023-10-17 | — | — | US | disclosed |
| WO-2022195454-A1 | PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2022-09-22 | — | — | WO | disclosed |