Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.74 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203733 | 0.91 | CYP1A2 (0.78) | CYP1A2SCN5ADYRK1ACLK2HASPIN | |
| SCHEMBL26539083 | 0.88 | CYP1A2 (0.83) | CYP1A2SCN5ADYRK1ACLK2HASPIN | |
| SCHEMBL26539084 | 0.88 | CYP1A2 (0.83) | CYP1A2SCN5ADYRK1ACLK2HASPIN | |
| SCHEMBL26539055 | 0.88 | CYP1A2 (0.83) | CYP1A2SCN5ADYRK1ACLK2HASPIN | |
| SCHEMBL23571320 | 0.85 | CYP1A2 (1.00) | CYP1A2SCN5ADYRK1ACLK2HASPIN | |
| SCHEMBL20203794 | 0.85 | CYP1A2 (1.00) | CYP1A2SCN5ADYRK1ACLK2HASPIN | |
| SCHEMBL20203758 | 0.85 | CYP1A2 (1.00) | CYP1A2SCN5ADYRK1ACLK2HASPIN | |
| SCHEMBL26539001 | 0.83 | CYP1A2 (0.52) | CYP1A2SCN5ADYRK1ACLK2HASPIN | |
| SCHEMBL26539195 | 0.79 | CYP1A2 (0.49) | CYP1A2SCN5ASCN1ASCN2A | |
| SCHEMBL26539109 | 0.77 | CYP1A2 (0.64) | CYP1A2SCN5ADYRK1ACLK2HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | CYP1A2 1988/4885SCN5A 8/4885DYRK1A 4493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.