Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26539127 | 0.96 | CYP1A2 (0.55) | CYP1A2FGFR1FGFR4SCN5AOPRM1 | |
| SCHEMBL20203847 | 0.93 | CYP1A2 (0.59) | CYP1A2FGFR1FGFR4SCN5AMAP4K4 | |
| SCHEMBL20203933 | 0.89 | CYP1A2 (0.64) | CYP1A2SCN5A | |
| SCHEMBL26539111 | 0.80 | CYP1A2 (0.79) | CYP1A2SCN5A | |
| SCHEMBL26539135 | 0.79 | CYP1A2 (0.46) | CYP1A2FGFR1FGFR4SCN5A | |
| SCHEMBL26539108 | 0.76 | CYP1A2 (0.59) | CYP1A2SCN5A | |
| SCHEMBL20209010 | 0.76 | CYP1A2 (0.54) | CYP1A2FGFR1FGFR4SCN5AMAP4K4 | |
| SCHEMBL938060 | 0.76 | CYP1A2 (0.60) | CYP1A2SCN5AMAP4K4 | |
| SCHEMBL26462170 | 0.75 | CYP1A2 (0.46) | CYP1A2FGFR1FGFR4MAP4K4OPRM1 | |
| SCHEMBL20189522 | 0.75 | CYP1A2 (0.50) | CYP1A2FGFR1FGFR4SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | CYP1A2 1988/4885FGFR1 3176/4885FGFR4 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.