Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644108 | 1.00 | KCNH2 (0.71) | KCNH2GCK | |
| SCHEMBL2644111 | 1.00 | KCNH2 (0.71) | KCNH2GCK | |
| SCHEMBL2644106 | 1.00 | KCNH2 (0.71) | KCNH2GCK | |
| SCHEMBL2644112 | 1.00 | KCNH2 (0.71) | KCNH2GCK | |
| SCHEMBL2664479 | 0.92 | KCNH2 (0.75) | KCNH2GCK | |
| SCHEMBL2645648 | 0.92 | KCNH2 (0.75) | KCNH2GCK | |
| SCHEMBL2644341 | 0.92 | KCNH2 (0.75) | KCNH2GCK | |
| SCHEMBL2664453 | 0.91 | KCNH2 (0.70) | KCNH2GCK | |
| SCHEMBL2644312 | 0.90 | KCNH2 (0.69) | KCNH2GCK | |
| SCHEMBL2644308 | 0.90 | KCNH2 (0.69) | KCNH2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572670-A1 | 5-SUBSTITUTED-PYRAZINE OR -PYRIDINE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-14 | — | — | EP | claimed |
| WO-2004052869-A1 | 5-SUBSTITUTED-PYRAZINE OR PYRIDINE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-24 | — | — | WO | claimed |
| EP-1572670-A1 | 5-SUBSTITUTED-PYRAZINE OR -PYRIDINE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004052869-A1 | 5-SUBSTITUTED-PYRAZINE OR PYRIDINE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-24 | — | — | WO | disclosed |