Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203981 | 0.92 | SCN5A (0.59) | CYP1A2SCN5AMAPTMAPK1KDM4E | |
| SCHEMBL26539445 | 0.89 | CYP1A2 (0.49) | CYP1A2SCN5AMAPTMAPK1KDM4E | |
| SCHEMBL26539423 | 0.85 | SCN5A (0.52) | CYP1A2SCN5AMAPTMAPK1KDM4E | |
| SCHEMBL26539453 | 0.84 | SCN5A (0.51) | CYP1A2SCN5AMAPTMAPK1KDM4E | |
| SCHEMBL26539323 | 0.81 | CYP1A2 (0.49) | CYP1A2SCN5ADYRK1AL3MBTL1SCN1A | |
| SCHEMBL26539436 | 0.80 | CYP1A2 (0.47) | CYP1A2SCN5AMAPTMAPK1KDM4E | |
| SCHEMBL26539437 | 0.79 | CYP1A2 (0.46) | CYP1A2SCN5AMAPTMAPK1KDM4E | |
| SCHEMBL20190642 | 0.79 | SCN5A (0.60) | CYP1A2SCN5AMAPTMAPK1KDM4E | |
| SCHEMBL20203718 | 0.79 | SCN5A (0.60) | CYP1A2SCN5AMAPTMAPK1KDM4E | |
| SCHEMBL26539119 | 0.78 | CYP1A2 (0.59) | CYP1A2SCN5ADYRK1AL3MBTL1SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | CYP1A2 1988/4885SCN5A 8/4885MAPT 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.