Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30088853 | 0.93 | MEN1 (0.46) | USP30RECQLNR1H2HPGDMEN1 | |
| SCHEMBL21564475 | 0.92 | RECQL (0.46) | USP30RECQLKDM4EPKMHPGD | |
| SCHEMBL27105268 | 0.88 | USP30 (0.43) | USP30RECQLNR1H2KDM4EPKM | |
| SCHEMBL10202840 | 0.85 | USP30 (0.43) | USP30RECQLNR1H2KDM4EHPGD | |
| SCHEMBL21564458 | 0.83 | RECQL (0.45) | USP30RECQLKDM4EPKMHPGD | |
| SCHEMBL25424422 | 0.80 | USP2 (0.43) | USP30RECQLNR1H2KDM4EHPGD | |
| SCHEMBL25739512 | 0.80 | USP2 (0.43) | USP30RECQLNR1H2KDM4EHPGD | |
| SCHEMBL24393399 | 0.80 | NR1H2 (0.38) | USP30RECQLNR1H2USP2SMN1; SMN2 | |
| SCHEMBL24392565 | 0.79 | NR1H2 (0.46) | USP30RECQLNR1H2MEN1ALDH1A1 | |
| SCHEMBL18901865 | 0.78 | NR1H2 (0.53) | RECQLNR1H2KDM4EPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023187715-A1 | COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2023-10-05 | — | — | WO | disclosed |