SCHEMBL26543398

SCHEMBL26543398

Brc1ccc2c(c1)[nH]c1c2c2ccccc2c2c3ccccc3c3ccccc3c12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 5/20 0.56
CCND1 P24385 5/20 0.56
CCNB2 O95067 4/20 0.56
CDK1 P06493 4/20 0.56
CCNB1 P14635 4/20 0.56
CCNB3 Q8WWL7 4/20 0.56
CCNE2 O96020 3/20 0.56
CCNE1 P24864 3/20 0.56
CDK2 P24941 3/20 0.56
CDK5 Q00535 3/20 0.56
CDK5R1 Q15078 3/20 0.56
CAMK2B Q13554 2/20 0.56
CAMK2G Q13555 2/20 0.56
CAMK2D Q13557 2/20 0.56
CAMK2A Q9UQM7 2/20 0.56
CCNT1 O60563 1/20 0.56
EIF2AK2 P19525 1/20 0.56
CCNA2 P20248 1/20 0.56
CDK9 P50750 1/20 0.56
CHEK1 O14757 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899929 0.91 CDK4 (0.57) CDK4CCND1CCNB2CDK1CCNB1
SCHEMBL2627633 0.89 CDK4 (0.52) CDK4CCND1CCNB2CDK1CCNB1
SCHEMBL22066486 0.83 CDK4 (0.54) CDK4CCND1CCNB2CDK1CCNB1
SCHEMBL2627638 0.82 CCNB2 (0.59) CDK4CCND1CCNB2CDK1CCNB1
SCHEMBL18668485 0.81 CDK4 (0.55) CDK4CCND1CCNB2CDK1CCNB1
SCHEMBL2627625 0.78 CDK4 (0.51) CDK4CCND1CCNB2CDK1CCNB1
SCHEMBL12003777 0.77 AR (0.58) CDK4CCND1CCNB2CDK1CCNB1
SCHEMBL5879261 0.76 CHEK1 (0.59) CDK4CCND1CCNB2CDK1CCNB1
SCHEMBL18758421 0.76 CCNB2 (0.49) CDK4CCND1CCNB2CDK1CCNB1
SCHEMBL20712203 0.75 CCNB2 (0.59) CDK4CCND1CCNB2CDK1CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2023-05-04 US disclosed
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, ODC1, OTC CDK4 2892/4885CCND1 1419/4885CCNB2 1924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.