Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2653939 | 0.90 | KCNH2 (0.70) | KCNH2GCK | |
| SCHEMBL2653936 | 0.90 | KCNH2 (0.70) | KCNH2GCK | |
| SCHEMBL2653925 | 0.88 | GCK (0.52) | KCNH2GCK | |
| SCHEMBL2644585 | 0.88 | KCNH2 (0.71) | KCNH2GCK | |
| SCHEMBL2644587 | 0.88 | KCNH2 (0.71) | KCNH2GCK | |
| SCHEMBL2645248 | 0.86 | KCNH2 (0.77) | KCNH2GCK | |
| SCHEMBL2645246 | 0.86 | KCNH2 (0.77) | KCNH2GCK | |
| SCHEMBL14431473 | 0.85 | KCNH2 (0.72) | KCNH2GCK | |
| SCHEMBL2644463 | 0.85 | KCNH2 (0.74) | KCNH2GCK | |
| SCHEMBL2644464 | 0.85 | KCNH2 (0.74) | KCNH2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572670-A1 | 5-SUBSTITUTED-PYRAZINE OR -PYRIDINE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004052869-A1 | 5-SUBSTITUTED-PYRAZINE OR PYRIDINE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-24 | — | — | WO | disclosed |