Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 15/20 | 0.35 |
| ▸ | JAK1 | P23458 | 9/20 | 0.35 |
| ▸ | JAK2 | O60674 | 9/20 | 0.33 |
| ▸ | RET | P07949 | 4/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | PRKX | P51817 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 3/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | MARK3 | P27448 | 2/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.31 |
| ▸ | STK3 | Q13188 | 2/20 | 0.31 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16731051 | 1.00 | JAK3 (0.35) | JAK3JAK1JAK2RETROCK1 | |
| SCHEMBL1848016 | 0.82 | JAK3 (0.48) | JAK3JAK1JAK2RETROCK1 | |
| SCHEMBL3685041 | 0.82 | JAK3 (0.48) | JAK3JAK1JAK2RETROCK1 | |
| Hydrochloric Acid SCHEMBL1847847 | 0.81 | JAK3 (0.47) | JAK3JAK1JAK2RETROCK1 | |
| SCHEMBL20343675 | 0.78 | PHGDH (0.36) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL22173652 | 0.74 | PHGDH (0.42) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL27562892 | 0.71 | JAK3 (0.36) | JAK3JAK1JAK2RETROCK1 | |
| SCHEMBL27616265 | 0.69 | JAK3 (0.36) | JAK3MEN1ALDH1A1KMT2A | |
| SCHEMBL13505197 | 0.69 | JAK3 (0.48) | JAK3JAK1JAK2RETROCK1 | |
| SCHEMBL3687009 | 0.68 | POLB (0.47) | JAK3MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604322-B1 | LACTULOSE GLYCOSIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | FRUITHY HOLDINGS LTD (CN) | 2023-10-18 | — | — | EP | disclosed |