Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16467279 | 0.93 | GCK (0.56) | GCK | |
| SCHEMBL16467506 | 0.93 | GCK (0.48) | GCKKDR | |
| Hydrochloric Acid SCHEMBL2657431 | 0.93 | GCK (0.56) | GCK | |
| SCHEMBL16467256 | 0.91 | GCK (0.54) | GCK | |
| SCHEMBL16467449 | 0.90 | GCK (0.48) | GCKKDR | |
| SCHEMBL16467519 | 0.89 | GCK (0.44) | GCKKDR | |
| SCHEMBL12126520 | 0.88 | GCK (0.49) | GCKKDR | |
| SCHEMBL16467426 | 0.88 | GCK (0.51) | GCKKDR | |
| SCHEMBL16467381 | 0.88 | GCK (0.45) | GCKKDR | |
| SCHEMBL1329338 | 0.87 | GCK (0.49) | GCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013204-B1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2015-02-18 | — | — | EP | claimed |
| EP-2173745-A2 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | Array Biopharma, Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2008118718-A2 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2008-10-02 | — | — | WO | disclosed |