Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 3/20 | 0.53 |
| ▸ | GCGR | P47871 | 19/20 | 0.47 |
| ▸ | GIPR | P48546 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655266 | 0.95 | GCG (0.55) | GCGGCGRGIPR | |
| SCHEMBL2654147 | 0.90 | FFAR1 (0.48) | GCGGCGRGIPR | |
| SCHEMBL3778469 | 0.89 | GCG (0.53) | GCGGCGRGIPR | |
| SCHEMBL2657520 | 0.89 | GCG (0.56) | GCGGCGRGIPR | |
| SCHEMBL2654634 | 0.85 | GCGR (0.48) | GCGGCGR | |
| SCHEMBL2650317 | 0.85 | GCG (0.49) | GCGGCGRGIPR | |
| SCHEMBL2269792 | 0.85 | GCGR (0.52) | GCGGCGRGIPR | |
| SCHEMBL2653386 | 0.85 | GCG (0.48) | GCGGCGRGIPR | |
| SCHEMBL2654285 | 0.84 | GCG (0.48) | GCGGCGRGIPR | |
| SCHEMBL2655270 | 0.84 | GCGR (0.53) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758853-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2005123668-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-29 | — | — | WO | claimed |
| EP-1758853-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123668-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-29 | — | — | WO | disclosed |