Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC18A2 | Q05940 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | STAT6 | P42226 | 2/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26554051 | 0.84 | SLC18A2 (0.35) | HTR1AOPRM1KCNH2TBXA2RPTGS1 | |
| SCHEMBL19075836 | 0.82 | MEN1 (0.50) | HTR1AOPRM1KCNH2SLC18A2MEN1 | |
| SCHEMBL19075837 | 0.82 | MEN1 (0.49) | HTR1AOPRM1KCNH2SLC18A2MEN1 | |
| SCHEMBL14135535 | 0.80 | MEN1 (0.53) | HTR1AOPRM1KCNH2SLC18A2MEN1 | |
| SCHEMBL15744675 | 0.79 | CYP3A4 (0.54) | HTR1AOPRM1KCNH2SLC18A2MEN1 | |
| SCHEMBL14135452 | 0.78 | SLC18A2 (0.54) | HTR1AOPRM1KCNH2SLC18A2MEN1 | |
| SCHEMBL15744729 | 0.77 | MEN1 (0.44) | HTR1AOPRM1KCNH2SLC18A2MEN1 | |
| SCHEMBL26404165 | 0.77 | SLC18A2 (0.33) | HTR1AOPRM1KCNH2SLC18A2MEN1 | |
| SCHEMBL15744736 | 0.75 | SLC18A2 (0.51) | HTR1AOPRM1KCNH2SLC18A2MEN1 | |
| SCHEMBL15744728 | 0.74 | MEN1 (0.41) | HTR1AOPRM1KCNH2SLC18A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330258-A1 | CONJUGATES COMPRISING A PHOSPHORUS (V) AND A DRUG MOIETY | TUBULIS GMBH (DE) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330258-A1 | CONJUGATES COMPRISING A PHOSPHORUS (V) AND A DRUG MOIETY | CALCR, BCR, PTH1R | HTR1A 2391/4885OPRM1 953/4885KCNH2 3775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.