Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2661610 | 0.88 | GCK (0.48) | GCK | |
| SCHEMBL1328138 | 0.85 | GCK (0.67) | GCK | |
| Hydrochloric Acid SCHEMBL1328392 | 0.84 | GCK (0.66) | GCK | |
| Hydrochloric Acid SCHEMBL2655531 | 0.83 | GCK (0.70) | GCK | |
| SCHEMBL1330130 | 0.83 | GCK (0.54) | GCK | |
| SCHEMBL1328248 | 0.82 | GCK (0.53) | GCK | |
| SCHEMBL1328261 | 0.82 | GCK (0.53) | GCK | |
| SCHEMBL1328966 | 0.79 | GCK (0.62) | GCK | |
| SCHEMBL2660211 | 0.78 | GCK (0.63) | GCK | |
| SCHEMBL1329061 | 0.78 | GCK (0.47) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013204-A2 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | Array Biopharma, Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007117381-A9 | 2 -AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2008-03-27 | — | — | WO | disclosed |
| WO-2007117381-A2 | 2 -AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2007-10-18 | — | — | WO | disclosed |