Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.46 |
| ▸ | GCG | P01275 | 1/20 | 0.45 |
| ▸ | GIPR | P48546 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 2/20 | 0.42 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2654697 | 0.91 | GCGR (0.55) | GCGRGCGGIPRPPARDPPARA | |
| SCHEMBL2653860 | 0.90 | GCGR (0.44) | GCGRGCGGIPRVIPR2 | |
| SCHEMBL2654147 | 0.89 | FFAR1 (0.48) | GCGRGCGGIPRPPARDPPARA | |
| SCHEMBL2654049 | 0.86 | GCGR (0.47) | GCGRGIPRPPARDPPARA | |
| SCHEMBL2653538 | 0.85 | GCGR (0.51) | GCGRGCGGIPRGLP1RVIPR2 | |
| SCHEMBL2655024 | 0.84 | GCGR (0.51) | GCGRGCG | |
| SCHEMBL2654589 | 0.84 | GCGR (0.48) | GCGRGIPRPPARD | |
| SCHEMBL2655266 | 0.84 | GCG (0.55) | GCGRGCGGIPRGLP1R | |
| SCHEMBL2655056 | 0.84 | GCGR (0.47) | GCGRGCGGIPRPPARDPPARA | |
| SCHEMBL2656116 | 0.84 | GCGR (0.55) | GCGRGCGGIPRPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758853-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2005123668-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-29 | — | — | WO | claimed |