Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2658144 | 1.00 | GCK (0.68) | GCK | |
| SCHEMBL2655350 | 0.98 | GCK (0.67) | GCK | |
| SCHEMBL2659119 | 0.98 | GCK (0.67) | GCK | |
| SCHEMBL2657035 | 0.91 | GCK (0.57) | GCK | |
| SCHEMBL2658397 | 0.91 | GCK (0.57) | GCK | |
| SCHEMBL2657711 | 0.90 | GCK (0.54) | GCK | |
| SCHEMBL2657695 | 0.89 | GCK (0.55) | GCK | |
| SCHEMBL2656671 | 0.89 | GCK (0.55) | GCK | |
| SCHEMBL2657973 | 0.88 | GCK (0.56) | GCK | |
| SCHEMBL2656863 | 0.88 | GCK (0.56) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091947-A2 | GLUCOKINASE ACTIVATORS | Takeda San Diego, Inc. (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2008079787-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2008-07-03 | — | — | WO | claimed |
| EP-2091947-A2 | GLUCOKINASE ACTIVATORS | Takeda San Diego, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008079787-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2008-07-03 | — | — | WO | disclosed |