Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 11/20 | 1.00 |
| ▸ | KDM1A | O60341 | 1/20 | 0.70 |
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2656318 | 1.00 | GCGR (1.00) | GCGRKDM1AMAOAMAOBMEN1 | |
| SCHEMBL32675194 | 0.92 | GCGR (0.84) | GCGRMEN1KMT2ANPC1 | |
| SCHEMBL24185310 | 0.92 | GCGR (0.84) | GCGRMEN1KMT2ANPC1 | |
| SCHEMBL2663737 | 0.88 | GCGR (1.00) | GCGRMEN1KMT2APOLB | |
| SCHEMBL2664128 | 0.87 | GCGR (0.77) | GCGRMEN1KMT2ANPC1SIRT1 | |
| SCHEMBL32675182 | 0.86 | GCGR (0.75) | GCGRMEN1KMT2ANPC1 | |
| SCHEMBL24185041 | 0.86 | GCGR (0.75) | GCGRMEN1KMT2ANPC1 | |
| SCHEMBL7236708 | 0.85 | GCGR (0.74) | GCGRKDM1AMAOAMAOBMEN1 | |
| SCHEMBL9072085 | 0.84 | GCGR (1.00) | GCGRMEN1KMT2ANPC1 | |
| SCHEMBL2663881 | 0.84 | GCGR (1.00) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |