Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 12/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931229 | 1.00 | GCK (0.42) | GCKPPARACCR5 | |
| SCHEMBL2647802 | 1.00 | GCK (0.42) | GCKPPARACCR5 | |
| SCHEMBL2647404 | 1.00 | GCK (0.42) | GCKPPARACCR5 | |
| SCHEMBL2647402 | 1.00 | GCK (0.42) | GCKPPARACCR5 | |
| SCHEMBL1931231 | 1.00 | GCK (0.42) | GCKPPARACCR5 | |
| SCHEMBL2659437 | 0.93 | GCK (0.47) | GCKPPARA | |
| SCHEMBL2659612 | 0.93 | GCK (0.47) | GCKPPARA | |
| SCHEMBL13609539 | 0.90 | GCK (0.40) | GCKPPARA | |
| SCHEMBL13609540 | 0.90 | GCK (0.40) | GCKPPARA | |
| SCHEMBL2676265 | 0.89 | PPARA (0.38) | GCKPPARACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824835-A1 | HETEROAROMATIC GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006058923-A1 | HETEROAROMATIC GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2006-06-08 | — | — | WO | disclosed |