⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527995 | 1.00 | — | — | |
| SCHEMBL13668063 | 1.00 | — | — | |
| SCHEMBL9962284 | 0.88 | MEN1 (0.33) | — | |
| SCHEMBL19940584 | 0.77 | POLB (0.31) | — | |
| SCHEMBL19465304 | 0.77 | MCL1 (0.32) | — | |
| SCHEMBL13644767 | 0.75 | — | — | |
| SCHEMBL21625940 | 0.74 | — | — | |
| SCHEMBL12927148 | 0.72 | — | — | |
| SCHEMBL13644763 | 0.72 | — | — | |
| SCHEMBL21471255 | 0.72 | MCL1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016953-A1 | TARGETED DELIVERY OF NICOTINAMINDE ADENINE DINUCLEOTIDE SALVAGE PATHWAY INHIBITORS | SEAGEN INC (US) | 2024-01-18 | — | — | US | disclosed |
| US-11638762-B2 | Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors | SEAGEN INC. (US) | 2023-05-02 | — | — | US | disclosed |