Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26121784 | 0.86 | PARP1 (0.70) | PARP1 | |
| SCHEMBL26123915 | 0.76 | PARP1 (0.62) | PARP1 | |
| SCHEMBL30546079 | 0.76 | PARP1 (0.62) | PARP1 | |
| SCHEMBL4440359 | 0.75 | PARP1 (1.00) | PARP1 | |
| SCHEMBL1824686 | 0.74 | PARP1 (0.86) | PARP1 | |
| SCHEMBL30546228 | 0.74 | PARP1 (0.60) | PARP1 | |
| SCHEMBL26124715 | 0.74 | PARP1 (0.60) | PARP1 | |
| SCHEMBL1689488 | 0.73 | PARP1 (1.00) | PARP1 | |
| SCHEMBL30415984 | 0.73 | PARP1 (1.00) | PARP1 | |
| SCHEMBL77530 | 0.73 | PARP1 (0.75) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |