⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26557647 | 0.94 | — | — | |
| SCHEMBL29362856 | 0.94 | — | — | |
| Trifluoroacetic Acid SCHEMBL29360614 | 0.91 | — | — | |
| SCHEMBL25230646 | 0.86 | — | — | |
| SCHEMBL25230634 | 0.86 | — | — | |
| SCHEMBL25230638 | 0.86 | — | — | |
| SCHEMBL26565879 | 0.86 | — | — | |
| SCHEMBL26557655 | 0.85 | KDM1A (0.32) | — | |
| SCHEMBL25205716 | 0.84 | — | — | |
| SCHEMBL29359451 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330249-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION OF BRM AND METHODS THEREOF | GENENTECH, INC. (US) | 2023-10-19 | — | — | US | disclosed |