Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268484 | 0.88 | CHRM3 (0.53) | CHRM3CHRM2 | |
| SCHEMBL3761050 | 0.86 | CHRM3 (0.53) | CHRM3 | |
| SCHEMBL710631 | 0.86 | CHRM3 (0.59) | CHRM3 | |
| SCHEMBL265767 | 0.85 | CHRM3 (0.51) | CHRM3 | |
| SCHEMBL3761046 | 0.83 | CHRM3 (0.52) | CHRM3 | |
| SCHEMBL5278240 | 0.83 | CHRM3 (0.52) | CHRM3CHRM2 | |
| SCHEMBL714031 | 0.82 | CHRM3 (0.53) | CHRM3CHRM2 | |
| SCHEMBL3763192 | 0.82 | CHRM3 (0.59) | CHRM3 | |
| SCHEMBL645761 | 0.82 | CHRM3 (0.59) | CHRM3 | |
| SCHEMBL3301257 | 0.81 | CHRM3 (0.52) | CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133905-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-8124627-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2012-02-28 | — | — | US | disclosed |