Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26568257 | 1.00 | MGAM (0.35) | MGAMCA1CA2GAASI | |
| SCHEMBL15695732 | 0.87 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL13106594 | 0.87 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL2018821 | 0.87 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL12889366 | 0.87 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL17827504 | 0.74 | MGAM (0.36) | MGAMCA1CA2GAASI | |
| SCHEMBL5546539 | 0.74 | MGAM (0.36) | MGAMCA1CA2GAASI | |
| SCHEMBL1320292 | 0.74 | MGAM (0.36) | MGAMCA1CA2GAASI | |
| SCHEMBL7153517 | 0.74 | MGAM (0.36) | MGAMCA1CA2GAASI | |
| SCHEMBL1321477 | 0.74 | MGAM (0.36) | MGAMCA1CA2GAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331649-A1 | INHIBITORS OF PROTEIN FUCOSYLATION AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2023-10-19 | — | — | US | disclosed |
| US-20230331649-A1 | INHIBITORS OF PROTEIN FUCOSYLATION AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331649-A1 | INHIBITORS OF PROTEIN FUCOSYLATION AND USES THEREOF | FUCA2, FUCA1, FANCI | MGAM 2386/4885CA1 2607/4885CA2 2379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.