Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22808 | 1.00 | GCK (0.51) | GCK | |
| SCHEMBL12990086 | 0.94 | GCK (0.52) | GCK | |
| SCHEMBL21806 | 0.94 | GCK (0.52) | GCK | |
| Hydrochloric Acid SCHEMBL2658489 | 0.94 | GCK (0.51) | GCK | |
| Hydrochloric Acid SCHEMBL3008820 | 0.94 | GCK (0.51) | GCK | |
| SCHEMBL12989546 | 0.92 | GCK (0.58) | GCK | |
| SCHEMBL22945 | 0.92 | GCK (0.58) | GCK | |
| Hydrochloric Acid SCHEMBL2661916 | 0.91 | GCK (0.57) | GCK | |
| SCHEMBL12989110 | 0.89 | GCK (0.53) | GCK | |
| SCHEMBL2661849 | 0.89 | GCK (0.53) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2209778-A1 | PYRIDIN-2 -YL-AMINO-I, 2, 4 -THIADIAZOLE DERIVATIVES AS GLUCOKINASE ACTIVATORS FOR THE TREATMENT OF DIABETES MELLITUS | Array Biopharma, Inc. (US) | 2010-07-28 | — | — | EP | disclosed |
| WO-2009042435-A1 | PYRIDIN-2 -YL-AMINO-I, 2, 4 -THIADIAZOLE DERIVATIVES AS GLUCOKINASE ACTIVATORS FOR THE TREATMENT OF DIABETES MELLITUS | ARRAY BIOPHARMA INC. (US) | 2009-04-02 | — | — | WO | disclosed |