Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.81 |
| ▸ | RARA | P10276 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2656697 | 0.89 | GCK (0.81) | GCKRARARARBRARG | |
| SCHEMBL2657449 | 0.89 | GCK (0.81) | GCKRARARARBRARG | |
| SCHEMBL14505791 | 0.89 | GCK (1.00) | GCKRARARARBRARG | |
| SCHEMBL2657270 | 0.89 | GCK (0.79) | GCKRARARARBRARG | |
| SCHEMBL16674411 | 0.88 | GCK (0.78) | GCKRARARARBRARG | |
| SCHEMBL2664885 | 0.88 | GCK (0.78) | GCKRARARARBRARG | |
| SCHEMBL2662202 | 0.87 | GCK (0.77) | GCKRARARARBRARG | |
| SCHEMBL2669719 | 0.87 | GCK (0.77) | GCKRARARARBRARG | |
| SCHEMBL12021286 | 0.86 | GCK (0.76) | GCKRARARARBRARG | |
| Hydrochloric Acid SCHEMBL2656226 | 0.86 | GCK (0.76) | GCKRARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185570-A2 | NOVEL ACTIVATORS OF GLUCOKINASE | Metabasis Therapeutics, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009023718-A2 | NOVEL ACTIVATORS OF GLUCOKINASE | METABASIS THERAPEUTICS, INC. (US) | 2009-02-19 | — | — | WO | disclosed |