Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021725 | 0.97 | GCK (0.57) | GCKKCNH2 | |
| SCHEMBL2658311 | 0.93 | GCK (0.60) | GCKKCNH2 | |
| SCHEMBL15580334 | 0.93 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL2657633 | 0.90 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL2656661 | 0.87 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL2669976 | 0.86 | GCK (0.63) | GCKKCNH2 | |
| SCHEMBL12021731 | 0.84 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL12021735 | 0.84 | GCK (0.57) | GCKKCNH2 | |
| SCHEMBL12021750 | 0.84 | GCK (0.62) | GCKKCNH2 | |
| SCHEMBL2657061 | 0.84 | GCK (0.72) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185570-A2 | NOVEL ACTIVATORS OF GLUCOKINASE | Metabasis Therapeutics, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009023718-A2 | NOVEL ACTIVATORS OF GLUCOKINASE | METABASIS THERAPEUTICS, INC. (US) | 2009-02-19 | — | — | WO | disclosed |