SCHEMBL2657243

SCHEMBL2657243

O=C(Nc1n[c]c(F)s1)C(Oc1ccc(F)cc1F)c1ccc(S(=O)(=O)C2CCCC2)cc1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2656766 0.97 GCK (0.69) GCK
SCHEMBL2657345 0.92 GCK (0.61) GCK
SCHEMBL2657322 0.91 GCK (0.60) GCK
SCHEMBL2658315 0.88 GCK (0.65) GCK
SCHEMBL2656974 0.86 GCK (0.60) GCK
SCHEMBL16456824 0.86 GCK (0.60) GCK
SCHEMBL2656416 0.85 GCK (0.73) GCK
SCHEMBL2657421 0.85 GCK (0.65) GCK
SCHEMBL2657952 0.84 GCK (0.71) GCK
SCHEMBL2657105 0.84 GCK (0.61) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2195304-A2 ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS Advinus Therapeutics Private Limited (IN) 2010-06-16 EP disclosed
WO-2009047798-A2 ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) 2009-04-16 WO disclosed