SCHEMBL26574255

SCHEMBL26574255

Cc1cc(-c2nn3c(c2-n2ccn(-c4ccc5c(cnn5C)c4)c2=O)CN(C(=O)c2cc4cc(C5CCOCC5)ccc4n2C2(C(=O)O)CC2C)CC3)cc(C)c1F

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404445 1.00 GLP1R (0.58) GLP1R
SCHEMBL26185729 1.00 GLP1R (0.58) GLP1R
SCHEMBL24276759 0.93 GLP1R (0.55) GLP1R
SCHEMBL30461922 0.92 GLP1R (0.49) GLP1R
SCHEMBL29049710 0.92 GLP1R (0.49) GLP1R
SCHEMBL29049709 0.92 GLP1R (0.49) GLP1R
SCHEMBL26185727 0.92 GLP1R (0.57) GLP1R
SCHEMBL24277154 0.92 GLP1R (0.57) GLP1R
SCHEMBL29406127 0.92 GLP1R (0.57) GLP1R
SCHEMBL24277046 0.90 GLP1R (0.54) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331732-A1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO, INC. 2023-10-19 — — US disclosed
US-20230331732-A1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO, INC. 2023-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331732-A1 HETEROCYCLIC GLP-1 AGONISTS GLP1R, GIPR, GCGR GLP1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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