Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515764 | 0.93 | GCK (0.54) | GCK | |
| SCHEMBL2517228 | 0.90 | GCK (0.56) | GCK | |
| SCHEMBL2517237 | 0.86 | GCK (0.52) | GCK | |
| SCHEMBL2518491 | 0.85 | GCK (0.51) | GCK | |
| SCHEMBL2516341 | 0.83 | GCK (0.49) | GCK | |
| SCHEMBL2517462 | 0.82 | GCK (0.53) | GCK | |
| SCHEMBL2518467 | 0.82 | GCK (0.65) | GCK | |
| SCHEMBL1712118 | 0.76 | GCK (0.79) | GCK | |
| SCHEMBL1712121 | 0.76 | GCK (0.79) | GCK | |
| SCHEMBL2518716 | 0.76 | GCK (0.68) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001875-A2 | GLUCOKINASE ACTIVATORS | Takeda San Diego, Inc. (US) | 2008-12-17 | — | — | EP | claimed |
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | claimed |
| EP-2001875-A2 | GLUCOKINASE ACTIVATORS | Takeda San Diego, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |